IDH1 - isocitrate dehydrogenase (NADP(+)) 1 Gene

Bos taurus

Also known as IDPc

Gene ID: 281235 | Gene type: protein coding

About IDH1

Primary_assembly 2: 96,510,261-96,532,002 reverse strand.ARS-UCD1.2:CM008169.2

This gene has 1 transcript (splice variant), 233 orthologues and 1 paralogue.

mRNA	Protein	Name
NM_181012.3	NP_851355.2	isocitrate dehydrogenase [NADP] cytoplasmic

PTZ00435

Protein Preferred Names

Protein Names

isocitrate dehydrogenase [NADP] cytoplasmic

IDH	IDP
NADP(+)-specific ICDH	cytosolic NADP-isocitrate dehydrogenase
isocitrate dehydrogenase (NADP(+)) 1, cytosolic	isocitrate dehydrogenase 1 (NADP+), soluble
oxalosuccinate decarboxylase

Approval

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-18767	Ivosidenib	Inhibitor	99.89%	Yes
HY-104042	Vorasidenib	Inhibitor	99.76%	Yes

Clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Phase
HY-114226	Olutasidenib	Inhibitor	99.16%	Phase 2
HY-104036	IDH-305	Inhibitor	99.15%	Phase 2
HY-145594	Safusidenib	Inhibitor	99.05%	Phase 2
HY-100020	BAY-1436032	Inhibitor	99.79%	Phase 1
HY-131312	Crelosidenib	Inhibitor	/	Phase 1

Pre-clinical Phase

Bioactive Molecules (20)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-18082	AGI-5198	Inhibitor	99.93%	Unkown
HY-19540	GSK864	Inhibitor	99.91%	Unkown
HY-128661	IDH1 Inhibitor 2	Inhibitor	98.70%	Unkown
HY-112056	DIM-C-pPhCO2Me	Inhibitor	99.47%	Unkown
HY-128888	(R,R)-GSK321	Inhibitor	99.36%	Unkown
HY-12475	Mutant IDH1-IN-1	Inhibitor	99.43%	Unkown
HY-128888B	(S,R)-GSK321	Control	98.62%	Unkown
HY-18717	Mutant IDH1-IN-2	Inhibitor	98.50%	Unkown
HY-150238	IDH1 Inhibitor 7	Inhibitor	99.46%	Unkown
HY-110144	TC-E 5008	Inhibitor	/	Unkown
HY-123153	GSK990	Control	/	Unkown
HY-149359	IHMT-IDH1-053	Inhibitor	/	Unkown
HY-158319	Mutant IDH1/NAMPT-IN-1	Inhibitor	/	Unkown
HY-121916	ML309	Inhibitor	/	Unkown
HY-175213	Mutant IDH1-IN-7	Inhibitor	/	Unkown
HY-175770	mIDH1-IN-2	Inhibitor	/	Unkown
HY-120765	BRD2879	Inhibitor	/	Unkown
HY-100476	Mutant IDH1-IN-3	Inhibitor	/	Unkown
HY-162631	IDH1 Inhibitor 9	Inhibitor	/	Unkown
HY-131312A	Crelosidenib gentisate	Inhibitor	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	IDH1	NCBI	NCBI:3417

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