MKX - mohawk homeobox Gene

Also Known as IFRX; IRXL1; C10orf48

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 283078

About MKX

Cytogenetic location: 10p12.1 Genomic coordinates (GRCh38): 10:27,672,874-27,745,819 (from NCBI)

This gene has 4 transcripts (splice variants), 279 orthologues and 6 paralogues. Biased expression in prostate (RPKM 5.8), ovary (RPKM 4.5) and 13 other tissues.

Summary

The protein encoded by this gene is an IRX family-related homeobox protein that may play a role in cell adhesion. Studies in mice suggest that this protein may be a regulator of tendon development. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Jun 2011]

MKX Products (2)

mRNA Protein Name
NM_001242702.2 NP_001229631.1 homeobox protein Mohawk
NM_173576.3 NP_775847.2 homeobox protein Mohawk

MKX Protein Structure

Homeobox_KN

Homeobox_KN: Homeobox KN domain (88 - 127)

  • 0
  • 100
  • 200
  • 300
  • 352 a.a.
Protein Preferred Names Protein Names

homeobox protein Mohawk

  • Iroquois family related homeodomain protein

Related Diseases

Diseases Alias
Smallpox
  • Variola

  • Ordinary Smallpox

  • Alastrim

  • Amaas

Shoulder Impingement Syndrome
  • Impingement Syndrome Of Shoulder Region

  • Subacromial Impingement

Spondylosis
  • Lumbar Spondylosis With Myelopathy

  • Lumbosacral Spondylosis Without Myelopathy

  • Spondylogenic Compression Of Lumbar Spinal Cord

  • Spondylogenic Compression Of Thoracic Spinal Cord

  • Spondylosis With Myelopathy

  • Thoracic Or Lumbar Spondylosis With Myelopathy

Cleft Palate, Isolated
  • Cleft Palate

  • Isolated Cleft Palate

  • CPI

  • Cp

  • Palatoschisis

  • Cleft Palate Isolated

  • Uranostaphyloschisis

  • Congenital Fissure Of Palate

  • Cleft Of Secondary Palate

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus MKX VGNC VGNC:31493
Rattus norvegicus MKX RGD RGD:1305652
Felis catus MKX VGNC VGNC:63521
Mus musculus MKX MGD MGI:2687286
Macaca mulatta MKX VGNC VGNC:74813