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PRTG - protogenin Gene

Also Known as IGDCC5

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 283659

About PRTG

Cytogenetic location: 15q21.3 Genomic coordinates (GRCh38): 15:55,611,544-55,743,152 (from NCBI)

This gene has 6 transcripts (splice variants), 201 orthologues and 36 paralogues. Biased expression in thyroid (RPKM 4.7), endometrium (RPKM 1.7) and 7 other tissues.

Summary

This gene encodes a member of the immunoglobulin superfamily. The encoded transmembrane protein has been associated with the development of various tissues, especially neurogenesis. It has been suggested that this gene may be associated with attention deficit hyperactivity disorder (ADHD). [provided by RefSeq, Nov 2014]

PRTG Products (1)

mRNA	Protein	Name
NM_173814.6	NP_776175.2	protogenin precursor

PRTG Protein Structure

I-set

fn3

0
200
400
600
800
1000
1150 a.a.

Protein Preferred Names	Protein Names
protogenin	immunoglobulin superfamily, DCC subclass, member 5

Related Diseases

Diseases	Alias
Orofacial Cleft 5	OFC5 Cleft Lip With Or Without Cleft Palate, Nonsyndromic, 5 Nonsyndromic Cleft Lip With Or Without Cleft Palate 5 Non-Syndromic Orofacial Cleft 5 Non-Syndromic Cleft Lip/Palate 5 Non-Syndromic Cleft Lip With Or Without Cleft Palate 5 Orofacial Cleft, Type 5
Orofacial Cleft 10	OFC10 Cleft Lip With Or Without Cleft Palate, Nonsyndromic, 10 Nonsyndromic Cleft Lip With Or Without Cleft Palate 10 Non-Syndromic Orofacial Cleft 10 Non-Syndromic Cleft Lip/Palate 10 Non-Syndromic Cleft Lip With Or Without Cleft Palate 10 Orofacial Cleft, Type 10
Orofacial Cleft 11	OFC11 Cleft Lip With Or Without Cleft Palate, Nonsyndromic, 11 Nonsyndromic Cleft Lip With Or Without Cleft Palate 11 Non-Syndromic Orofacial Cleft 11 Chcl Cleft Lip Congenital Healed Congenital Healed Cleft Lip Non-Syndromic Cleft Lip/Palate 11 Non-Syndromic Cleft Lip With Or Without Cleft Palate 11 Orofacial Cleft, Type 11 Cleft Lip, Congenital Healed
Attention Deficit-Hyperactivity Disorder	Attention Deficit Hyperactivity Disorder ADHD Attention Deficit Disorder Attention Deficit-Hyperactivity Disorder, Susceptibility To Attention Deficit Disorder With Hyperactivity Hyperkinetic Disorder Hyperactivity Of Childhood Attention-Deficit/Hyperactivity Disorder Add Addh Attention Deficit Attention Deficit Disorder Of Childhood With Hyperactivity Attention Deficit Disorder With Hyperactivity Syndrome Hyperkinetic Syndrome Attention-Deficit Hyperactivity Disorder Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type Disturbance Of Activity And Attention Disorder Of Activity And Attention Adhd - [Attention Deficit Hyperactivity Disorder] Hyperkinetic Disorders Disorder Of Activity And Attention With Hyperkinesia Attention Deficit Syndrome With Hyperactivity
Orofacial Cleft 15	OFC15 Non-Syndromic Orofacial Cleft 15

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11261	PRTG Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	PRTG	VGNC	VGNC:55137
Felis catus	PRTG	VGNC	VGNC:64405
Mus musculus	PRTG	MGD	MGI:2444710
Rattus norvegicus	PRTG	RGD	RGD:1307157
Macaca mulatta	PRTG	VGNC	VGNC:76321
Canis familiaris	PRTG	VGNC	VGNC:45076
Others	PRTG	NCBI