PLA2G4D - phospholipase A2 group IVD Gene

Homo sapiens

Also known as cPLA2delta

Gene ID: 283748 | Gene type: protein coding

About PLA2G4D

Cytogenetic location: 15q15.1 Genomic coordinates (GRCh38): 15:42,067,009-42,094,562 (from NCBI)

This gene has 3 transcripts (splice variants), 140 orthologues and 5 paralogues. Biased expression in skin (RPKM 6.8), prostate (RPKM 6.7) and 2 other tissues.

Summary

The Phospholipase A2 Enzyme family, including PLA2G4D, catalyze the hydrolysis of glycerophospholipids at the sn-2 position and then liberate free fatty acids and lysophospholipids (Chiba et al., 2004 [PubMed 14709560]).[supplied by OMIM, Jun 2009]

PLA2G4D Products(1)

mRNA	Protein	Name
NM_178034.4	NP_828848.3	cytosolic phospholipase A2 delta

PLA2G4D Protein Structure

PLA2_B

0
200
400
600
818 a.a.

Protein Preferred Names

Protein Names

cytosolic phospholipase A2 delta

cPLA2-delta

Related Diseases

Diseases

Alias

Dyskeratosis Congenita, Autosomal Recessive 2

DKCB2	Autosomal Recessive Dyskeratosis Congenita 2
Dyskeratosis Congenita, Autosomal Recessive, 2	Dyskeratosis Congenita, Autosomal Recessive, Type 2

Immunodeficiency 29

Mendelian Susceptibility To Mycobacterial Diseases Due To Complete Il12b Deficiency	IMD29
Il12b Deficiency	Immunodeficiency 29, Mycobacteriosis
Mendelian Susceptibility To Mycobacterial Diseases Due To Complete Interleukin 12b Deficiency	Msmd Due To Complete Il12b Deficiency
Msmd Due To Complete Interleukin 12b Deficiency	Immunodeficiency, Type 29, Mycobacteriosis

Oliver-Mcfarlane Syndrome

Trichomegaly-Retina Pigmentary Degeneration-Dwarfism Syndrome	OMCS
Long Eyelashes-Intellectual Disability Syndrome	Trichomegaly With Mental Retardation, Dwarfism, And Pigmentary Degeneration Of Retina
Eyelashes, Long, With Mental Retardation	Eyelashes Long Mental Retardation
Trichomegaly With Intellectual Disability, Dwarfism And Pigmentary Degeneration	Trichomegaly With Intellectual Disability, Dwarfism And Pigmentary Degeneration Of Retina
Eyelashes, Long With Intellectual Disability	Oliver Mcfarlane Syndrome
Congenital Trichomegaly, Pigmentary Retinal Degeneration, And Short Stature	Trichomegaly, Retina Pigmentary Degeneration, Dwarfism
Trichomegaly Retina Pigmentary Degeneration Dwarfism

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10629	PLA2G4D Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	PLA2G4D	VGNC	VGNC:44627
Bos taurus	PLA2G4D	VGNC	VGNC:32961
Felis catus	PLA2G4D	VGNC	VGNC:64200
Mus musculus	PLA2G4D	MGD	MGI:1925640
Macaca mulatta	PLA2G4D	VGNC	VGNC:76136
Rattus norvegicus	PLA2G4D	RGD	RGD:1593372

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