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TPRX1 - tetrapeptide repeat homeobox 1 Gene

Also Known as TPRX

生物種: Homo sapiens

遺伝子タイプ: protein coding

遺伝子ID: 284355

About TPRX1

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:47,801,232-47,819,051 (from NCBI)

This gene has 3 transcripts (splice variants), 9 orthologues and 1 paralogue. Low expression observed in reference dataset.

Summary

Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 Amino acids referred to as the homeodomain. This gene is a member of the TPRX homeobox gene family. [provided by RefSeq, Jul 2008]

TPRX1 Products (2)

mRNA	Protein	Name
NM_001397346.1	NP_001384275.1	tetra-peptide repeat homeobox protein 1 isoform 1
NM_198479.3	NP_940881.3	tetra-peptide repeat homeobox protein 1 isoform 2

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	参考文献	由来
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	36074823	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

Biological Process GO Annotation	Evidence	参考文献	由来
involved in maternal-to-zygotic transition of gene expression	IDA IDA: Inferred from direct assay	36074823	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
tetra-peptide repeat homeobox protein 1	CRX like homeobox 2

Diseases	Alias
Congenital Muscular Dystrophy-Dystroglycanopathy Type A5	Congenital Muscular Dystrophy-Dystroglycanopathy With Brain And Eye Anomalies Type A5 Mddga5 Walker-Warburg Syndrome Or Muscle-Eye-Brain Disease, Fkrp-Related

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-RS14951	TPRX1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown