TPRX1 - tetrapeptide repeat homeobox 1 Gene

Also Known as TPRX

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 284355

About TPRX1

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:47,801,232-47,819,051 (from NCBI)

This gene has 3 transcripts (splice variants), 9 orthologues and 1 paralogue. Low expression observed in reference dataset.

Summary

Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 Amino acids referred to as the homeodomain. This gene is a member of the TPRX homeobox gene family. [provided by RefSeq, Jul 2008]

TPRX1 Products (2)

mRNA Protein Name
NM_001397346.1 NP_001384275.1 tetra-peptide repeat homeobox protein 1 isoform 1
NM_198479.3 NP_940881.3 tetra-peptide repeat homeobox protein 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
36074823 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
involved in maternal-to-zygotic transition of gene expression IDA
IDA: Inferred from direct assay
36074823 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tetra-peptide repeat homeobox protein 1

  • CRX like homeobox 2

Related Diseases

Diseases Alias
Congenital Muscular Dystrophy-Dystroglycanopathy Type A5

  • Congenital Muscular Dystrophy-Dystroglycanopathy With Brain And Eye Anomalies Type A5

  • Mddga5

  • Walker-Warburg Syndrome Or Muscle-Eye-Brain Disease, Fkrp-Related
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14951 TPRX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown