LPAR4 - lysophosphatidic acid receptor 4 Gene
Also Known as LPA4; P2Y9; GPR23; P2RY9; P2Y5-LIKE
Species: Homo sapiens
About LPAR4
This gene has 4 transcripts (splice variants), 174 orthologues, 16 paralogues and is associated with 1 phenotype. Low expression observed in reference dataset.
Summary
This gene encodes a member of the lysophosphatidic acid receptor family. It may also be related to the P2Y receptors, a family of receptors that bind purine and pyrimidine nucleotides and are coupled to G proteins. The encoded protein may play a role in monocytic differentiation. [provided by RefSeq, Feb 2009]
LPAR4 Products (10)
| mRNA | Protein | Name |
|---|---|---|
| XM_047442015.1 | XP_047297971.1 | lysophosphatidic acid receptor 4 isoform X1 |
| XM_006724639.4 | XP_006724702.1 | lysophosphatidic acid receptor 4 isoform X1 |
| XM_047442014.1 | XP_047297970.1 | lysophosphatidic acid receptor 4 isoform X1 |
| XM_017029437.2 | XP_016884926.1 | lysophosphatidic acid receptor 4 isoform X1 |
| NM_001278000.3 | NP_001264929.1 | lysophosphatidic acid receptor 4 |
| NM_005296.3 | NP_005287.1 | lysophosphatidic acid receptor 4 |
| XM_047442011.1 | XP_047297967.1 | lysophosphatidic acid receptor 4 isoform X1 |
| XM_017029438.2 | XP_016884927.1 | lysophosphatidic acid receptor 4 isoform X1 |
| XM_047442013.1 | XP_047297969.1 | lysophosphatidic acid receptor 4 isoform X1 |
| XM_047442012.1 | XP_047297968.1 | lysophosphatidic acid receptor 4 isoform X1 |
LPAR4 Protein Structure
7tm_1: 7 transmembrane receptor (rhodopsin family) (57 - 311)
- 0
- 100
- 200
- 300
- 370 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
lysophosphatidic acid receptor 4 |
|
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Differentiated Thyroid Carcinoma |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Canis familiaris | LPAR4 | VGNC | VGNC:42745 |
| Rattus norvegicus | LPAR4 | RGD | RGD:1563686 |
| Mus musculus | LPAR4 | MGD | MGI:1925384 |
| Bos taurus | LPAR4 | VGNC | VGNC:30958 |
| Macaca mulatta | LPAR4 | VGNC | VGNC:74418 |
| Others | LPAR4 | NCBI |