1. Gene
  2. FBXO43 - F-box protein 43 Gene

FBXO43 - F-box protein 43 Gene

Homo sapiens (human)

Also known as EMI2; ERP1; FBX43; OOMD12; SPGF64; OZEMA12

Gene ID: 286151 | Gene type: protein coding

About FBXO43

Summary

Members of the F-box protein family, such as FBXO43, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through Other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

FBXO43 Products(1)

mRNA Protein Name
XM_011516990.2 XP_011515292.1 F-box only protein 43 isoform X2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of cell cycle process IMP
IMP: Inferred from mutant phenotype
34052850 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

F-box only protein 43

early mitotic inhibitor 2

endogenous meiotic inhibitor 2