Poglut1 - protein O-glucosyltransferase 1 Gene

Also known as Ktelc1; RGD1306248

About Poglut1

Summary

Predicted to enable UDP-glucosyltransferase activity and UDP-xylosyltransferase activity. Predicted to be involved in several processes, including positive regulation of Notch signaling pathway; protein O-linked glycosylation via serine; and regulation of gastrulation. Predicted to act upstream of or within several processes, including paraxial mesoderm development; regulation of Notch signaling pathway; and somitogenesis. Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in endomembrane system. Human ortholog(s) of this gene implicated in Dowling-Degos disease and autosomal recessive limb-girdle muscular dystrophy type 2Z. Orthologous to human POGLUT1 (protein O-glucosyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]