Mtm1 - myotubularin 1 Gene

Predicted to enable intermediate filament binding activity; Phosphatase activity; and phosphatidylinositol binding activity. Predicted to be involved in several processes, including dephosphorylation; mitochondrion organization; and muscle cell cellular homeostasis. Predicted to act upstream of or within negative regulation of intracellular signal transduction; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; and positive regulation of skeletal muscle tissue growth. Predicted to be located in several cellular components, including I band; late endosome; and ruffle. Predicted to be active in cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in centronuclear myopathy X-linked and congenital structural myopathy. Orthologous to human MTM1 (myotubularin 1). [provided by Alliance of Genome Resources, Apr 2022]