2. Gene
  3. Spta1 - spectrin, alpha, erythrocytic 1 Gene

Spta1 - spectrin, alpha, erythrocytic 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Spna1

Gene ID: 289257 | Gene type: protein coding

About Spta1

Summary

Predicted to enable actin filament binding activity. Predicted to be involved in actin Cytoskeleton organization. Predicted to act upstream of or within several processes, including lymphocyte homeostasis; porphyrin-containing compound biosynthetic process; and positive regulation of T cell proliferation. Located in axon and cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in hereditary spherocytosis and hereditary spherocytosis type 3. Orthologous to human SPTA1 (spectrin alpha, erythrocytic 1). [provided by Alliance of Genome Resources, Apr 2022]

Spta1 Products(1)

mRNA Protein Name
NM_001011908.4 NP_001011908.3 spectrin alpha chain, erythrocytic 1
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in axon IDA
IDA: Inferred from direct assay
11684331 RGD
located in cytoplasmic side of plasma membrane IDA
IDA: Inferred from direct assay
11684331 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

spectrin alpha chain, erythrocytic 1

erythroid spectrin alpha

spectrin alpha chain, erythrocyte

spectrin, alpha, erythrocytic 1 (elliptocytosis 2)

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13729 SPTA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22829 Spta1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Spta1 NCBI NCBI:6708