SLC6A16 - solute carrier family 6 member 16 Gene
Also Known as NT5; NTT5
Species: Homo sapiens
About SLC6A16
This gene has 7 transcripts (splice variants), 58 orthologues and 19 paralogues. Biased expression in testis (RPKM 36.6) and ovary (RPKM 1.3).
Summary
SLC6A16 shows structural characteristics of an Na(+)- and Cl(-)-dependent neurotransmitter transporter, including 12 transmembrane (TM) domains, intracellular N and C termini, and large extracellular loops containing multiple N-glycosylation sites.[supplied by OMIM, Mar 2008]
SLC6A16 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_014037.3 | NP_054756.2 | orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 |
SLC6A16 Protein Structure
SNF: Sodium:neurotransmitter symporter family (103 - 683)
- 0
- 200
- 400
- 600
- 736 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Brain Glioblastoma Multiforme |
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| Phototoxic Dermatitis |
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| Hartnup Disorder |
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| Iminoglycinuria |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Macaca mulatta | SLC6A16 | VGNC | VGNC:77692 |
| Bos taurus | SLC6A16 | VGNC | VGNC:52249 |
| Canis familiaris | SLC6A16 | VGNC | VGNC:53986 |
| Rattus norvegicus | SLC6A16 | RGD | RGD:1561338 |
| Mus musculus | SLC6A16 | MGD | MGI:2685930 |
| Others | SLC6A16 | NCBI |