2. Gene
  3. Pdlim2 - PDZ and LIM domain 2 Gene

Pdlim2 - PDZ and LIM domain 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 290354 | Gene type: protein coding

About Pdlim2

Summary

Enables filamin binding activity; muscle alpha-actinin binding activity; and Myosin heavy chain binding activity. Predicted to be involved in actin Cytoskeleton organization; heart development; and muscle structure development. Colocalizes with cortical actin Cytoskeleton and stress fiber. Orthologous to human PDLIM2 (PDZ and LIM domain 2). [provided by Alliance of Genome Resources, Apr 2022]

Pdlim2 Products(1)

mRNA Protein Name
NM_001007622.1 NP_001007623.1 PDZ and LIM domain protein 2
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables alpha-actinin binding IPI
IPI: Inferred from physical interaction
15505042 RGD
enables filamin binding IPI
IPI: Inferred from physical interaction
15505042 RGD
enables muscle alpha-actinin binding IPI
IPI: Inferred from physical interaction
15505042 RGD
enables myosin heavy chain binding IPI
IPI: Inferred from physical interaction
15505042 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
15505042 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cortical actin cytoskeleton IDA
IDA: Inferred from direct assay
15505042 RGD
located in stress fiber IDA
IDA: Inferred from direct assay
15505042 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

PDZ and LIM domain protein 2

alpha-actinins and filamin-interacting protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10280 PDLIM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdlim2 NCBI NCBI:64236