Erlin2 - ER lipid raft associated 2 Gene

Rattus norvegicus

Also known as Spfh2; RGD1309010

Gene ID: 290823 | Gene type: protein coding

About Erlin2

Summary

Predicted to enable Cholesterol binding activity and ubiquitin protein Ligase binding activity. Predicted to be involved in SREBP signaling pathway; negative regulation of lipid biosynthetic process; and ubiquitin-dependent ERAD pathway. Predicted to be located in several cellular components, including cytosol; endoplasmic reticulum; and membrane raft. Predicted to be part of protein-containing complex. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 18. Orthologous to human ERLIN2 (ER lipid raft associated 2). [provided by Alliance of Genome Resources, Apr 2022]

Erlin2 Products(1)

mRNA	Protein	Name
NM_001106088.2	NP_001099558.1	erlin-2

Protein Preferred Names

Protein Names

erlin-2

SPFH domain family, member 2	SPFH domain-containing protein 2
endoplasmic reticulum lipid raft-associated protein 2	stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04502	ERLIN2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Erlin2	NCBI	NCBI:11160

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