Tubb2b - tubulin, beta 2B class IIb Gene

Also Known as Tubb2; RGD1309427

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 291081

Summary

Predicted to enable GTP binding activity and protein heterodimerization activity. Predicted to be a structural constituent of Cytoskeleton. Involved in neuron migration. Predicted to be located in microtubule Cytoskeleton. Predicted to be active in Schaffer collateral - CA1 synapse; cytoplasm; and microtubule. Human ortholog(s) of this gene implicated in complex cortical dysplasia with Other brain malformations 7. Orthologous to human TUBB2B (tubulin beta 2B class IIb). [provided by Alliance of Genome Resources, Apr 2022]

Tubb2b Products (1)

mRNA Protein Name
NM_001013886.2 NP_001013908.2 tubulin beta-2B chain

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in neuron migration IMP
IMP: Inferred from mutant phenotype
19465910 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tubulin beta-2B chain

  • beta-tubulin T beta15 (aa 1-445)

  • t beta-15

  • tubulin, beta 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15253 TUBB2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tubb2b NCBI NCBI:347733