Aldh5a1 - aldehyde dehydrogenase 5 family, member A1 Gene

Also Known as Ssadh

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 291133

Summary

Enables NAD binding activity; carboxylic acid binding activity; and succinate-semialdehyde dehydrogenase (NAD+) activity. Involved in succinate metabolic process. Located in mitochondrion. Human ortholog(s) of this gene implicated in succinic semialdehyde dehydrogenase deficiency. Orthologous to human ALDH5A1 (aldehyde dehydrogenase 5 family member A1). [provided by Alliance of Genome Resources, Apr 2022]

Aldh5a1 Products (1)

mRNA Protein Name
NM_022851.1 NP_074042.1 succinate-semialdehyde dehydrogenase, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables NAD binding IDA
IDA: Inferred from direct assay
7262085 RGD
enables carboxylic acid binding IPI
IPI: Inferred from physical interaction
7262085 RGD
enables succinate-semialdehyde dehydrogenase (NAD+) activity IDA
IDA: Inferred from direct assay
7262085 RGD
Biological Process GO Annotation Evidence References Source
involved in succinate metabolic process IDA
IDA: Inferred from direct assay
7262085 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

succinate-semialdehyde dehydrogenase, mitochondrial

  • NAD(+)-dependent succinic semialdehyde dehydrogenase

  • aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase)

  • aldehyde dehydrogenase family 5, subfamily A1

  • succinic semialdehyde dehydrogenase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00578 ALDH5A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20621 Aldh4a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aldh5a1 NCBI NCBI:7915