Dsg4 - desmoglein 4 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 291754

Summary

Enables calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to act upstream of or within BMP signaling pathway; hair follicle development; and keratinocyte differentiation. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in desmosome. Used to study hypotrichosis. Human ortholog(s) of this gene implicated in hypotrichosis and hypotrichosis 6. Orthologous to human DSG4 (desmoglein 4). [provided by Alliance of Genome Resources, Apr 2022]

Dsg4 Products (1)

mRNA Protein Name
NM_199490.2 NP_955784.1 desmoglein-4 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables calcium ion binding IMP
IMP: Inferred from mutant phenotype
15081105 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

desmoglein-4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04024 DSG4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19127 Dsg4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25617 Dsg4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dsg4 NCBI NCBI:147409