Tubb5 - tubulin, beta 5 class I Gene

Also Known as Tubb

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29214

Summary

Enables GTPase activating protein binding activity and protein domain specific binding activity. Predicted to be involved in microtubule Cytoskeleton organization; mitotic cell cycle; and regulation of synapse organization. Predicted to act upstream of or within spindle assembly. Located in membrane raft. Part of protein-containing complex. Human ortholog(s) of this gene implicated in complex cortical dysplasia with Other brain malformations 6 and congenital symmetric circumferential skin creases 1. Orthologous to human TUBB (tubulin beta class I). [provided by Alliance of Genome Resources, Apr 2022]

Tubb5 Products (1)

mRNA Protein Name
NM_173102.2 NP_775125.1 tubulin beta-5 chain

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTPase activating protein binding IPI
IPI: Inferred from physical interaction
16820281 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
18220421 RGD
enables protein domain specific binding IPI
IPI: Inferred from physical interaction
16820281 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
18220421 RGD
Cellular Component GO Annotation Evidence References Source
located in membrane raft IDA
IDA: Inferred from direct assay
14499952 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
18220421 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tubulin beta-5 chain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15250 TUBB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15257 TUBB6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown