2. Gene
  3. Eif3a - eukaryotic translation initiation factor 3, subunit A Gene

Eif3a - eukaryotic translation initiation factor 3, subunit A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as ZH12; Eif3s10

Gene ID: 292148 | Gene type: protein coding

About Eif3a

Summary

Enables receptor tyrosine kinase binding activity. Involved in negative regulation of ERK1 and ERK2 cascade. Located in microtubule and nucleus. Orthologous to human EIF3A (eukaryotic translation initiation factor 3 subunit A). [provided by Alliance of Genome Resources, Apr 2022]

Eif3a Products(1)

mRNA Protein Name
NM_001047087.2 NP_001040552.2 eukaryotic translation initiation factor 3 subunit A
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
24882364 RGD
enables receptor tyrosine kinase binding IPI
IPI: Inferred from physical interaction
10691301 RGD
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of ERK1 and ERK2 cascade IMP
IMP: Inferred from mutant phenotype
22025682 RGD
Cellular Component GO Annotation Evidence Reference Source
located in microtubule IDA
IDA: Inferred from direct assay
22613460 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

eukaryotic translation initiation factor 3 subunit A

eIF-3-theta

eukaryotic translation initiation factor 3 subunit 10

eukaryotic translation initiation factor 3, subunit 10 (theta)

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04289 EIF6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04257 EIF3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eif3a NCBI NCBI:8661