Eif3a - eukaryotic translation initiation factor 3, subunit A Gene

Also Known as ZH12; Eif3s10

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 292148

Summary

Enables receptor tyrosine kinase binding activity. Involved in negative regulation of ERK1 and ERK2 cascade. Located in microtubule and nucleus. Orthologous to human EIF3A (eukaryotic translation initiation factor 3 subunit A). [provided by Alliance of Genome Resources, Apr 2022]

Eif3a Products (1)

mRNA Protein Name
NM_001047087.2 NP_001040552.2 eukaryotic translation initiation factor 3 subunit A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24882364 RGD
enables receptor tyrosine kinase binding IPI
IPI: Inferred from physical interaction
10691301 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of ERK1 and ERK2 cascade IMP
IMP: Inferred from mutant phenotype
22025682 RGD
Cellular Component GO Annotation Evidence References Source
located in microtubule IDA
IDA: Inferred from direct assay
22613460 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

eukaryotic translation initiation factor 3 subunit A

  • eIF-3-theta

  • eukaryotic translation initiation factor 3 subunit 10

  • eukaryotic translation initiation factor 3, subunit 10 (theta)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04289 EIF6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04257 EIF3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eif3a NCBI NCBI:8661