Cpeb1 - cytoplasmic polyadenylation element binding protein 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 293056

Summary

Enables mRNA 3'-UTR binding activity. Involved in several processes, including cellular response to lipopolysaccharide; mRNA transport; and regulation of macromolecule biosynthetic process. Located in several cellular components, including centrosome; growth cone; and postsynaptic density. Used to study glioblastoma. Biomarker of portal hypertension and primary biliary cholangitis. Orthologous to human CPEB1 (cytoplasmic polyadenylation element binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Cpeb1 Products (1)

mRNA Protein Name
NM_001106276.1 NP_001099746.1 cytoplasmic polyadenylation element-binding protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables mRNA 3'-UTR binding IDA
IDA: Inferred from direct assay
20603120 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
21620800 RGD
involved in mRNA transport IMP
IMP: Inferred from mutant phenotype
12629046 RGD
involved in negative regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
21865454 RGD
involved in negative regulation of translation IMP
IMP: Inferred from mutant phenotype
23360795 RGD
involved in positive regulation of cell migration IMP
IMP: Inferred from mutant phenotype
23360795 RGD
involved in positive regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
19864575 RGD
involved in positive regulation of nitric-oxide synthase biosynthetic process IMP
IMP: Inferred from mutant phenotype
21620800 RGD
involved in positive regulation of translation IMP
IMP: Inferred from mutant phenotype
19864575 RGD
Cellular Component GO Annotation Evidence References Source
located in centrosome IDA
IDA: Inferred from direct assay
21865454 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
9856468 RGD
located in growth cone IDA
IDA: Inferred from direct assay
19864575 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
19864575 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
21865454 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
22727665 RGD
is active in postsynaptic density IDA
IDA: Inferred from direct assay
9856468 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytoplasmic polyadenylation element-binding protein 1

  • CPE-BP1

  • CPE-binding protein 1

  • CPEB

  • CPEB-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-145944 ASR-488 Inducer 99.73% Unkown
HY-RS03091 CPEB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cpeb1 NCBI NCBI:64506