Cpeb1 - cytoplasmic polyadenylation element binding protein 1 Gene

Rattus norvegicus

Gene ID: 293056 | Gene type: protein coding

About Cpeb1

Summary

Enables mRNA 3'-UTR binding activity. Involved in several processes, including cellular response to lipopolysaccharide; mRNA transport; and regulation of macromolecule biosynthetic process. Located in several cellular components, including centrosome; growth cone; and postsynaptic density. Used to study glioblastoma. Biomarker of portal hypertension and primary biliary cholangitis. Orthologous to human CPEB1 (cytoplasmic polyadenylation element binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Cpeb1 Products(1)

mRNA	Protein	Name
NM_001106276.1	NP_001099746.1	cytoplasmic polyadenylation element-binding protein 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables mRNA 3'-UTR binding	IDA IDA: Inferred from direct assay	20603120	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to lipopolysaccharide	IEP IEP: Inferred from expression pattern	21620800	RGD
involved in mRNA transport	IMP IMP: Inferred from mutant phenotype	12629046	RGD
involved in negative regulation of cell population proliferation	IMP IMP: Inferred from mutant phenotype	21865454	RGD
involved in negative regulation of translation	IMP IMP: Inferred from mutant phenotype	23360795	RGD
involved in positive regulation of cell migration	IMP IMP: Inferred from mutant phenotype	23360795	RGD
involved in positive regulation of neuron projection development	IMP IMP: Inferred from mutant phenotype	19864575	RGD
involved in positive regulation of nitric-oxide synthase biosynthetic process	IMP IMP: Inferred from mutant phenotype	21620800	RGD
involved in positive regulation of translation	IMP IMP: Inferred from mutant phenotype	19864575	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in centrosome	IDA IDA: Inferred from direct assay	21865454	RGD
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	9856468	RGD
located in growth cone	IDA IDA: Inferred from direct assay	19864575	RGD
located in neuronal cell body	IDA IDA: Inferred from direct assay	19864575	RGD
located in perinuclear region of cytoplasm	IDA IDA: Inferred from direct assay	21865454	RGD
is active in postsynapse	IDA IDA: Inferred from direct assay	22727665	RGD
is active in postsynaptic density	IDA IDA: Inferred from direct assay	9856468	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

cytoplasmic polyadenylation element-binding protein 1

CPE-BP1	CPE-binding protein 1
CPEB	CPEB-1

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-145944	ASR-488	Inducer	99.73%	Unkown
HY-RS03091	CPEB1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cpeb1	NCBI	NCBI:64506

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