2. Gene
  3. PPFIA1 - Ppfia1 PTPRF interacting protein alpha 1 Gene

PPFIA1 - Ppfia1 PTPRF interacting protein alpha 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 293645 | Gene type: protein coding

About PPFIA1

Summary

Predicted to be involved in synapse organization. Predicted to act upstream of or within negative regulation of protein localization to plasma membrane and negative regulation of stress fiber assembly. Located in axon and dendrite. Part of protein-containing complex. Orthologous to human PPFIA1 (PTPRF interacting protein alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

PPFIA1 Products(1)

mRNA Protein Name
NM_001106320.2 NP_001099790.2 liprin-alpha-1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IDA
IDA: Inferred from direct assay
11931740 RGD
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IMP
IMP: Inferred from mutant phenotype
11931740 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
11931740 RGD
is active in Schaffer collateral - CA1 synapse IMP
IMP: Inferred from mutant phenotype
11931740 RGD
located in axon IDA
IDA: Inferred from direct assay
12522103 RGD
located in dendrite IDA
IDA: Inferred from direct assay
12522103 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
12522103 RGD
is active in spine apparatus IDA
IDA: Inferred from direct assay
17419996 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

liprin-alpha-1

liprin-alpha-1-like

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein, alpha 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10939 PPFIA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PPFIA1 NCBI NCBI:8500