Chrne - cholinergic receptor nicotinic epsilon subunit Gene

Also Known as nAChR

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29422

Summary

Enables acetylcholine-gated cation-selective channel activity. Involved in cation transport and skeletal muscle contraction. Part of acetylcholine-gated channel complex. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 4A; congenital myasthenic syndrome 4B; and congenital myasthenic syndrome 4C. Orthologous to human CHRNE (cholinergic receptor nicotinic epsilon subunit). [provided by Alliance of Genome Resources, Apr 2022]

Chrne Products (1)

mRNA Protein Name
NM_017194.1 NP_058890.1 acetylcholine receptor subunit epsilon precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables acetylcholine-gated monoatomic cation-selective channel activity IDA
IDA: Inferred from direct assay
22461452 RGD
Biological Process GO Annotation Evidence References Source
involved in monoatomic cation transport IDA
IDA: Inferred from direct assay
22461452 RGD
involved in skeletal muscle contraction IDA
IDA: Inferred from direct assay
22461452 RGD
Cellular Component GO Annotation Evidence References Source
part of acetylcholine-gated channel complex IDA
IDA: Inferred from direct assay
22461452 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acetylcholine receptor subunit epsilon

  • acetylcholine receptor epsilon

  • cholinergic receptor, nicotinic epsilon

  • cholinergic receptor, nicotinic, epsilon (muscle)

  • cholinergic receptor, nicotinic, epsilon polypeptide

  • epsilon-subunit

  • gene for acetylcholine receptor epsilon subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02679 CHRNE Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Chrne NCBI NCBI:1145