2. Gene
  3. Chrne - cholinergic receptor nicotinic epsilon subunit Gene

Chrne - cholinergic receptor nicotinic epsilon subunit Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as nAChR

Gene ID: 29422 | Gene type: protein coding

About Chrne

Summary

Enables acetylcholine-gated cation-selective channel activity. Involved in cation transport and skeletal muscle contraction. Part of acetylcholine-gated channel complex. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 4A; congenital myasthenic syndrome 4B; and congenital myasthenic syndrome 4C. Orthologous to human CHRNE (cholinergic receptor nicotinic epsilon subunit). [provided by Alliance of Genome Resources, Apr 2022]

Chrne Products(1)

mRNA Protein Name
NM_017194.1 NP_058890.1 acetylcholine receptor subunit epsilon precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables acetylcholine-gated monoatomic cation-selective channel activity IDA
IDA: Inferred from direct assay
22461452 RGD
Biological Process GO Annotation Evidence Reference Source
involved in monoatomic cation transport IDA
IDA: Inferred from direct assay
22461452 RGD
involved in skeletal muscle contraction IDA
IDA: Inferred from direct assay
22461452 RGD
Cellular Component GO Annotation Evidence Reference Source
part of acetylcholine-gated channel complex IDA
IDA: Inferred from direct assay
22461452 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acetylcholine receptor subunit epsilon

acetylcholine receptor epsilon

cholinergic receptor, nicotinic epsilon

cholinergic receptor, nicotinic, epsilon (muscle)

cholinergic receptor, nicotinic, epsilon polypeptide

epsilon-subunit

gene for acetylcholine receptor epsilon subunit

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02679 CHRNE Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Chrne NCBI NCBI:1145