RT1-Da - RT1 class II, locus Da Gene

Also Known as DA1; H2-Ea; RT1-u

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 294269

Summary

Predicted to enable several functions, including MHC class II protein complex binding activity; T cell receptor binding activity; and peptide antigen binding activity. Predicted to be involved in several processes, including antigen processing and presentation of endogenous peptide antigen via MHC class II; antigen processing and presentation of exogenous peptide antigen via MHC class II; and regulation of T cell differentiation. Predicted to be located in bounding membrane of organelle; cell surface; and immunological synapse. Predicted to be part of MHC class II protein complex. Biomarker of prediabetes syndrome. Human ortholog(s) of this gene implicated in Parkinson's disease (multiple); allergic disease; asthma; and autoimmune disease (multiple). Orthologous to human HLA-DRA (major histocompatibility complex, class II, DR alpha). [provided by Alliance of Genome Resources, Apr 2022]

RT1-Da Products (1)

mRNA Protein Name
NM_001008847.2 NP_001008847.1 RT1 class II, locus Da precursor
Protein Preferred Names Protein Names

RT1 class II, locus Da

  • MHC RT1.u-D-alpha chain

  • MHC class II RT1D alpha chain antigen

  • MHC class II antigen RT1.D alpha chain

  • RT1-D alpha

  • RT1-Du alpha

  • histocompatibility 2, class II antigen E alpha