Sesn1 - sestrin 1 Gene

About Sesn1

Summary

Predicted to enable leucine binding activity and oxidoreductase activity, acting on peroxide as acceptor. Predicted to be involved in several processes, including cellular response to leucine; cellular response to starvation; and negative regulation of TORC1 signaling. Predicted to act upstream of or within regulation of protein kinase B signaling. Predicted to be located in cytoplasm; fibrillar center; and nucleoplasm. Predicted to be part of GATOR2 complex. Orthologous to human SESN1 (sestrin 1). [provided by Alliance of Genome Resources, Apr 2022]