Snx5 - sorting nexin 5 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 296199

Summary

Enables D1 Dopamine Receptor binding activity and phosphatidylinositol phosphate binding activity. Involved in epidermal growth factor catabolic process; negative regulation of blood pressure; and positive regulation of renal sodium excretion. Located in several cellular components, including brush border; cytosol; and endosome. Orthologous to human SNX5 (sorting nexin 5). [provided by Alliance of Genome Resources, Apr 2022]

Snx5 Products (1)

mRNA Protein Name
NM_001399298.1 NP_001386227.1 sorting nexin-5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables D1 dopamine receptor binding IDA
IDA: Inferred from direct assay
23195037 RGD
enables phosphatidylinositol binding IDA
IDA: Inferred from direct assay
19553671 RGD
enables phosphatidylinositol-3,5-bisphosphate binding IDA
IDA: Inferred from direct assay
16487940 RGD
enables phosphatidylinositol-4-phosphate binding IDA
IDA: Inferred from direct assay
16487940 RGD
enables phosphatidylinositol-5-phosphate binding IDA
IDA: Inferred from direct assay
16487940 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
16487940 RGD
Biological Process GO Annotation Evidence Références Source
involved in epidermal growth factor catabolic process IDA
IDA: Inferred from direct assay
16487940 RGD
involved in negative regulation of blood pressure IMP
IMP: Inferred from mutant phenotype
23195037 RGD
Cellular Component GO Annotation Evidence Références Source
located in brush border IDA
IDA: Inferred from direct assay
23195037 RGD
located in endosome IDA
IDA: Inferred from direct assay
16487940 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sorting nexin-5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS13544 SNX5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Snx5 NCBI NCBI:27131