Slc38a2 - solute carrier family 38, member 2 Gene

Also Known as Ata2; Sat2; Atrc2; Snat2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29642

Summary

Enables L-glutamine transmembrane transporter activity and L-serine transmembrane transporter activity. Involved in several processes, including cellular response to mechanical stimulus; glycine betaine transport; and neutral amino acid transport. Located in several cellular components, including brush border; neuronal cell body; and sarcolemma. Biomarker of visual epilepsy. Orthologous to human SLC38A2 (solute carrier family 38 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc38a2 Products (1)

mRNA Protein Name
NM_181090.3 NP_851604.2 sodium-coupled neutral amino acid symporter 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables L-glutamine transmembrane transporter activity IDA
IDA: Inferred from direct assay
15218073 RGD
enables L-serine transmembrane transporter activity IDA
IDA: Inferred from direct assay
15218073 RGD
enables acidic amino acid transmembrane transporter activity IDA
IDA: Inferred from direct assay
10811809 RGD
enables alanine:sodium symporter activity IDA
IDA: Inferred from direct assay
10811809 RGD
enables amino acid:sodium symporter activity IDA
IDA: Inferred from direct assay
12054432 RGD
enables neutral L-amino acid:sodium symporter activity IDA
IDA: Inferred from direct assay
10747860 RGD
enables proline:sodium symporter activity IDA
IDA: Inferred from direct assay
11716780 RGD
Biological Process GO Annotation Evidence References Source
involved in L-glutamine import across plasma membrane IDA
IDA: Inferred from direct assay
18832333 RGD
involved in L-proline import across plasma membrane IDA
IDA: Inferred from direct assay
11716780 RGD
involved in L-serine import across plasma membrane IDA
IDA: Inferred from direct assay
16629640 RGD
involved in L-serine transport IDA
IDA: Inferred from direct assay
15218073 RGD
involved in alanine transport IDA
IDA: Inferred from direct assay
10811809 RGD
involved in amino acid import IDA
IDA: Inferred from direct assay
11756489 RGD
involved in cellular response to amino acid starvation IEP
IEP: Inferred from expression pattern
11311116 RGD
involved in cellular response to mechanical stimulus IEP
IEP: Inferred from expression pattern
15288886 RGD
involved in cerebral cortex development IEP
IEP: Inferred from expression pattern
21718781 RGD
involved in female pregnancy IEP
IEP: Inferred from expression pattern
19892400 RGD
involved in glutamine transport IDA
IDA: Inferred from direct assay
15218073 RGD
involved in glycine betaine transport IDA
IDA: Inferred from direct assay
24434061 RGD
involved in neutral amino acid transport IDA
IDA: Inferred from direct assay
10747860 RGD
involved in regulation of glutamate secretion, neurotransmission IDA
IDA: Inferred from direct assay
18832333 RGD
involved in response to muscle activity IEP
IEP: Inferred from expression pattern
24016666 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
15561425 RGD
located in brush border IDA
IDA: Inferred from direct assay
20338592 RGD
located in dendrite IDA
IDA: Inferred from direct assay
21718781 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
15561425 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
11311116 RGD
located in sarcolemma IDA
IDA: Inferred from direct assay
11834730 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium-coupled neutral amino acid symporter 2

sodium-coupled neutral amino acid transporter 2

  • amino acid transporter A2

  • amino acid transporter cationic 2

  • amino acid transporter system A2

  • amino acid transporter, cationic 2 (low affinity)

  • system A amino acid transporter 2

  • system A transporter 1

  • system N amino acid transporter 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13220 SLC38A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22042 Slc38a2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc38a2 NCBI NCBI:54407