Bckdhb - branched chain keto acid dehydrogenase E1 subunit beta Gene

Also Known as BCKDE1B

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29711

Summary

Predicted to contribute to 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity. Involved in response to cAMP; response to glucocorticoid; and response to nutrient. Predicted to be located in mitochondrion and nucleolus. Predicted to be part of mitochondrial alpha-ketoglutarate dehydrogenase complex. Human ortholog(s) of this gene implicated in maple syrup urine disease. Orthologous to human BCKDHB (branched chain keto acid dehydrogenase E1 subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Bckdhb Products (1)

mRNA Protein Name
NM_019267.1 NP_062140.1 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
3619032 RGD
Biological Process GO Annotation Evidence References Source
involved in response to cAMP IEP
IEP: Inferred from expression pattern
8034710 RGD
involved in response to glucocorticoid IEP
IEP: Inferred from expression pattern
8034710 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
8109974 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

2-oxoisovalerate dehydrogenase subunit beta, mitochondrial

  • 2-oxoisovalerate dehydrogenase beta subunit

  • BCKDH E1-beta

  • branched chain keto acid dehydrogenase E1 beta

  • branched chain keto acid dehydrogenase E1, beta polypeptide

  • branched-chain alpha-keto acid dehydrogenase E1 component beta chain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01410 BCKDHB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bckdhb NCBI NCBI:594