Kcnj5 - potassium inwardly-rectifying channel, subfamily J, member 5 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29713

Summary

Predicted to enable inward rectifier Potassium Channel activity and voltage-gated Potassium Channel activity involved in atrial cardiac muscle cell action potential repolarization. Predicted to be involved in cardiac conduction; potassium ion import across plasma membrane; and regulation of ion transmembrane transport. Located in T-tubule and external side of plasma membrane. Human ortholog(s) of this gene implicated in atrial fibrillation; long QT syndrome 13; and primary hyperaldosteronism. Orthologous to human KCNJ5 (potassium inwardly rectifying channel subfamily J member 5). [provided by Alliance of Genome Resources, Apr 2022]

Kcnj5 Products (1)

mRNA Protein Name
NM_017297.2 NP_058993.1 G protein-activated inward rectifier potassium channel 4

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in T-tubule IDA
IDA: Inferred from direct assay
11561006 RGD
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
11561006 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

G protein-activated inward rectifier potassium channel 4

  • CIR

  • GIRK-4

  • GIRK4

  • KATP-1

  • cardiac inward rectifier

  • heart KATP channel

  • inward rectifier K(+) channel Kir3.4

  • potassium channel, inwardly rectifying subfamily J member 5

  • potassium voltage-gated channel subfamily J member 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07148 KCNJ5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcnj5 NCBI NCBI:3762