2. Gene
  3. Nkx2-8 - NK2 homeobox 8 Gene

Nkx2-8 - NK2 homeobox 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Nkx2-9

Gene ID: 299061 | Gene type: protein coding

About Nkx2-8

Summary

Enables sequence-specific DNA binding activity. Predicted to be involved in cell differentiation; positive regulation of transcription by RNA polymerase II; and transcription by RNA polymerase II. Predicted to act upstream of or within axonogenesis; lung development; and negative regulation of epithelial cell proliferation. Located in nucleus. Orthologous to human NKX2-8 (NK2 homeobox 8). [provided by Alliance of Genome Resources, Apr 2022]

Nkx2-8 Products(2)

mRNA Protein Name
NM_001106732.1 NP_001100202.1 homeobox protein Nkx-2.8
NM_001106732.1 NP_001100202.1 homeobox protein Nkx-2.8
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
12167706 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein Nkx-2.8

NK2 transcription factor related, locus 9

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09332 NKX2-8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nkx2-8 NCBI NCBI:26257