2. Gene
  3. Ttc8 - tetratricopeptide repeat domain 8 Gene

Ttc8 - tetratricopeptide repeat domain 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 299246 | Gene type: protein coding

About Ttc8

Summary

Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity. Predicted to be involved in establishment of anatomical structure orientation and non-motile cilium assembly. Predicted to act upstream of or within several processes, including morphogenesis of a polarized epithelium; negative regulation of GTPase activity; and nervous system development. Predicted to be located in centrosome; membrane; and photoreceptor connecting cilium. Predicted to be part of BBSome. Predicted to be active in ciliary basal body and non-motile cilium. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome; Bardet-Biedl syndrome 8; and retinitis pigmentosa 51. Orthologous to human TTC8 (tetratricopeptide repeat domain 8). [provided by Alliance of Genome Resources, Apr 2022]

Ttc8 Products(3)

mRNA Protein Name
NM_001106752.1 NP_001100222.1 tetratricopeptide repeat protein 8 isoform 2
NM_001399497.1 NP_001386426.1 tetratricopeptide repeat protein 8 isoform 1
NM_001399499.1 NP_001386428.1 tetratricopeptide repeat protein 8 isoform 3
Protein Preferred Names Protein Names

tetratricopeptide repeat protein 8

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15220 TTC8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ttc8 NCBI NCBI:123016