SLC25A24 - solute carrier family 25 member 24 Gene

Homo sapiens

Also known as APC1; SCAMC1; SCAMC-1

Gene ID: 29957 | Gene type: protein coding

About SLC25A24

Cytogenetic location: 1p13.3 Genomic coordinates (GRCh38): 1:108,134,043-108,200,343 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 189 orthologues, 49 paralogues and is associated with 4 phenotypes. Ubiquitous expression in small intestine (RPKM 21.4), colon (RPKM 20.9) and 25 other tissues.

Summary

This gene encodes a carrier protein that transports ATP-Mg exchanging it for phosphate. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

SLC25A24 Products(2)

mRNA	Protein	Name
NM_013386.5	NP_037518.3	calcium-binding mitochondrial carrier protein SCaMC-1 isoform 1
NM_213651.3	NP_998816.1	calcium-binding mitochondrial carrier protein SCaMC-1 isoform 2

SLC25A24 Protein Structure

EF-hand_7

Mito_carr

0
100
200
300
400
477 a.a.

Protein Preferred Names

Protein Names

calcium-binding mitochondrial carrier protein SCaMC-1

ATP-Mg/P(i) co-transporter 1

Related Diseases

Diseases

Alias

Fontaine Progeroid Syndrome

Gorlin-Chaudhry-Moss Syndrome	Gcms
Craniofacial Dysostosis, Hypertrichosis, Hypoplasia Of Labia Majora, Dental And Eye Anomalies, Patent Ductus Arteriosus, And Normal Intelligence	Gorlin Chaudhry Moss Syndrome
Gcm Syndrome	FPS
Progeroid Syndrome, Congenital, Petty Type	Progeroid Syndrome Petty Type
Craniofacial Dysostosis, Patent Ductus Arteriosus, Hypertrichosis, Hypoplasia Of Labia Majora, Dental And Eye Anomalies	Petty Laxova Wiedemann Syndrome
Progeroid Syndrome Congenital Petty Type	Craniofacial Dysostosis-Genital, Dental, Cardiac Anomalies Syndrome
Cranofacial Dysostosis-Hypertrichosis-Hypoplasia Of Labia Majora Syndrome	Dental And Eye Anomalies-Patent Ductus Arteriosus-Normal Intelligence Syndrome
Progeroid Syndrome, Petty Type	Petty Syndrome
Petty-Laxova-Wiedemann Syndrome

Progeroid Syndrome

Dementia

Dementias	Presenile Dementia
Alzheimer Type Dementia	Alzheimer Sclerosis
Alzheimer Disease Dementia	Alzheimer Dementia
Primary Degenerative Alzheimer Type Dementia	End Stage Alzheimer'S Dementia
Alzheimer'S Type Atypical Dementia	Alzheimer Type Presenile Dementia
Early Onset Alzheimer Dementia	Dementia In Alzheimer Disease Type 2
Dementia In Alzheimer Disease With Early Onset	Early Onset Alzheimer Type Dementia, Uncomplicated
Primary Degenerative Alzheimer Type Dementia, Early Onset	Primary Degenerative Alzheimer Type Dementia, Presenile Onset, Uncomplicated
Alzheimer Disease Dementia With Early Onset	Presenile Sclerosis
Presenile Brain Sclerosis	Presenile Alzheimer Brain Sclerosis
Late Onset Alzheimer Dementia	Dementia In Alzheimer Disease Type 1
Dementia In Alzheimer Disease With Late Onset	Primary Degenerative Alzheimer Type Dementia, Late Onset
Sdat - [Senile Dementia, Alzheimer Type]	Alzheimer Disease Dementia With Late Onset
Late Onset Alzheimer Brain Sclerosis	Senile Alzheimer Brain Disease
Senile Alzheimer Brain Sclerosis	Senile Primary Degenerative Alzheimer Type Dementia
Senile Dementia Of The Alzheimer Type	Arteriosclerotic Dementia
Strategic-Infarct Dementia	Post Stroke Dementia
Vascular Cognitive Impairment	Vascular Dementia
Dementia Of The Lewy Body Type	Dementia With Lewy Bodies
Sdlt - [Senile Dementia Of The Lewy Body Type]	Senile Dementia Of The Lewy Body Type
Alcohol-Related Dementia	Alcoholic Dementia Nos
Alcohol-Induced Dementia	Alcoholic Brain Syndrome
Chronic Alcoholic Brain Syndrome	Alcohol Dementia
Late Onset Alcoholic Psychosis	Residual And Late-Onset Alcohol-Induced Psychotic Disorder
Mental And Behavioural Disorders Due To Use Of Sedatives Or Hypnotics, Residual And Late-Onset Psychotic Disorder	Late-Onset Psychoactive Substance-Induced Psychotic Disorder
Inhalant Dementia	Volatile Solvents Dementia
Dementia In Paralysis Agitans	Pdd - [Parkinson Disease Dementia]
Dementia Syndrome Of Parkinson Disease	Dementia In Parkinson Disease
Parkinson Related Dementia	Dementia In Huntington Chorea
Hiv - [Human Immunodeficiency Virus] Dementia	Hiv- [Human Immunodeficiency Virus] Associated Cognitive Motor Complex
Hiv- [Human Immunodeficiency Virus] Associated Dementia Complex	Aids - [Acquired Immunodeficiency Syndrome] Dementia Complex
Aids Related Dementia	Dementia Due To Niacin Deficiency

Craniosynostosis

Premature Closure Of Cranial Sutures	Craniostenosis
Craniosynostosis Syndrome	Cso
Craniosynostoses	Congenital Ossification Of Cranial Sutures
Congenital Ossification Of Sutures Of Skull	Craniostosis
Imperfect Fusion Of Skull	Congenital Imperfect Closure Skull
Imperfect Closure Skull	Premature Closure Cranium Sutures
Deficiency Of Craniofacial Axis

Hypertrichosis

Conduct Disorder

Cecum Adenocarcinoma

Cecal Adenocarcinoma

Adenocarcinoma Of Cecum

Colon Mucinous Adenocarcinoma

Colonic Mucinous Adenocarcinoma

Mucinous Adenocarcinoma Of The Colon

Body Dysmorphic Disorder

Dysmorphophobia	Body Dysmorphia
Dysmorphic Syndrome	Body Dysmorphic Disorders

Umbilical Hernia

Hernia, Umbilical

Sengers Syndrome

Mitochondrial Dna Depletion Syndrome 10	Cardiomyopathy And Cataract
Cataract And Cardiomyopathy	MTDPS10
Congenital Cataract-Hypertrophic Cardiomyopathy-Mitochondrial Myopathy Syndrome	Cardiomyopathic Mitochondrial Dna Depletion Syndrome 10
Senger Syndrome

Myoclonic Epilepsy Associated With Ragged-Red Fibers

Merrf Syndrome	MERRF
Fukuhara Syndrome	Myoclonic Epilepsy Associated With Ragged Red Fibers
Myoencephalopathy Ragged-Red Fiber Disease	Myoclonic Epilepsy - Ragged Red Fibers
Myoclonus Epilepsy And Ragged Red Fibers	Myoclonus With Epilepsy And With Ragged Red Fibers
Myoclonic Epilepsy With Ragged Red Fibers	Myoclonic Epilepsy With Ragged-Red Fibers
Fukuhara Disease	Myoclonus Epilepsy Associated With Ragged-Red Fibres
Myoclonus With Epilepsy With Ragged Red Fibers

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13105	SLC25A24 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SLC25A24	VGNC	VGNC:54068
Mus musculus	SLC25A24	MGD	MGI:1917160
Macaca mulatta	SLC25A24	VGNC	VGNC:100140
Felis catus	SLC25A24	VGNC	VGNC:65265
Bos taurus	SLC25A24	VGNC	VGNC:55682
Rattus norvegicus	SLC25A24	RGD	RGD:1311982

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