2. Gene
  3. Nsmce2 - NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase Gene

Nsmce2 - NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1305156

Gene ID: 299957 | Gene type: protein coding

About Nsmce2

Summary

Predicted to enable SUMO Ligase activity. Predicted to be involved in several processes, including DNA recombination; positive regulation of cell cycle process; and protein sumoylation. Predicted to be located in PML body and chromosome, telomeric region. Predicted to be part of Smc5-Smc6 complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Seckel syndrome 10. Orthologous to human NSMCE2 (NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO Ligase). [provided by Alliance of Genome Resources, Apr 2022]

Nsmce2 Products(1)

mRNA Protein Name
NM_001024876.1 NP_001020047.1 E3 SUMO-protein ligase NSE2
Protein Preferred Names Protein Names

E3 SUMO-protein ligase NSE2

E3 SUMO-protein transferase NSE2

MMS21 homolog

non-SMC element 2 homolog

non-SMC element 2, MMS21 homolog

non-structural maintenance of chromosomes element 2 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09598 NSMCE2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nsmce2 NCBI NCBI:286053