2. Gene
  3. SORL1 - Sorl1 sortilin related receptor 1 Gene

SORL1 - Sorl1 sortilin related receptor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Lr11; SorLA; RGD619914

Gene ID: 300652 | Gene type: protein coding

About SORL1

Summary

Predicted to enable several functions, including low-density lipoprotein particle binding activity; peptide binding activity; and small GTPase binding activity. Involved in cell migration and cell population proliferation. Located in multivesicular body and neuronal cell body. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human SORL1 (sortilin related receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

SORL1 Products(1)

mRNA Protein Name
NM_053519.1 NP_445971.1 sortilin-related receptor precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in cell migration IMP
IMP: Inferred from mutant phenotype
11956127 RGD
Cellular Component GO Annotation Evidence Reference Source
located in multivesicular body IDA
IDA: Inferred from direct assay
16452683 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
10867025 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sortilin-related receptor

LDLR relative with 11 ligand-binding repeats

low-density lipoprotein receptor relative with 11 ligand-binding repeats

sortilin-related receptor, LDLR class A repeats-containing

sortilin-related receptor-like

sorting protein-related receptor containing

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13574 SORL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21763 Sorl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens SORL1 NCBI NCBI:6653