Pqbp1 - polyglutamine binding protein 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 302557

Summary

Enables protein C-terminus binding activity. Involved in positive regulation of non-motile cilium assembly. Located in centrosome; ciliary base; and nucleus. Human ortholog(s) of this gene implicated in Renpenning syndrome. Orthologous to human PQBP1 (polyglutamine binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Pqbp1 Products (1)

mRNA Protein Name
NM_001013957.2 NP_001013979.2 polyglutamine-binding protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTPase binding IPI
IPI: Inferred from physical interaction
23994472 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
23994472 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of non-motile cilium assembly IMP
IMP: Inferred from mutant phenotype
23994472 RGD
Cellular Component GO Annotation Evidence References Source
located in centrosome IDA
IDA: Inferred from direct assay
23994472 RGD
located in ciliary base IDA
IDA: Inferred from direct assay
23994472 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

polyglutamine-binding protein 1

  • PQBP-1

  • polyglutamine tract-binding protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11043 PQBP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pqbp1 NCBI NCBI:10084