Tbl1x - transducin (beta)-like 1 X-linked Gene

Also known as RGD1563868

About Tbl1x

Summary

Predicted to enable several functions, including beta-catenin binding activity; identical protein binding activity; and protein C-terminus binding activity. Predicted to be involved in several processes, including positive regulation of canonical Wnt signaling pathway; protein stabilization; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including fat cell differentiation; proteasome-mediated ubiquitin-dependent protein catabolic process; and response to estrogen. Predicted to be located in mitotic spindle and nucleus. Predicted to be part of histone deacetylase complex and transcription repressor complex. Human ortholog(s) of this gene implicated in Y-linked deafness 2 and congenital nongoitrous hypothyroidism 8. Orthologous to several human genes including TBL1X (transducin beta like 1 X-linked). [provided by Alliance of Genome Resources, Apr 2022]