Sgca - sarcoglycan, alpha Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 303468

Summary

Predicted to enable calcium ion binding activity. Involved in response to denervation involved in regulation of muscle adaptation and skeletal muscle tissue regeneration. Predicted to be located in cell-cell junction; membrane raft; and sarcolemma. Predicted to be part of sarcoglycan complex. Biomarker of muscular atrophy. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2D and muscular dystrophy. Orthologous to human SGCA (sarcoglycan alpha). [provided by Alliance of Genome Resources, Apr 2022]

Sgca Products (3)

mRNA Protein Name
NM_001107039.2 NP_001100509.1 alpha-sarcoglycan isoform 1 precursor
NM_001395600.1 NP_001382529.1 alpha-sarcoglycan isoform 2
NM_001395601.1 NP_001382530.1 alpha-sarcoglycan isoform 3

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in response to denervation involved in regulation of muscle adaptation IEP
IEP: Inferred from expression pattern
8906620 RGD
involved in skeletal muscle tissue regeneration IEP
IEP: Inferred from expression pattern
12086334 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-sarcoglycan

  • adhalin

  • sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)

  • sarcoglycan, alpha (dystrophin-associated glycoprotein)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12790 SGCA Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sgca NCBI NCBI:6442