Prdm8 - PR/SET domain 8 Gene

Predicted to enable chromatin binding activity; Histone Methyltransferase activity (H3-K9 specific); and transcription corepressor activity. Predicted to be involved in oligodendrocyte development and regulation of transcription, DNA-templated. Predicted to act upstream of or within central nervous system projection neuron axonogenesis; histone H3-K9 methylation; and negative regulation of transcription, DNA-templated. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 10. Orthologous to human PRDM8 (PR/SET domain 8). [provided by Alliance of Genome Resources, Apr 2022]