Cln8 - CLN8, transmembrane ER and ERGIC protein Gene

About Cln8

Summary

Predicted to enable ceramide binding activity. Predicted to be involved in several processes, including ceramide metabolic process; Cholesterol metabolic process; and lipid homeostasis. Predicted to act upstream of or within several processes, including adult walking behavior; glutamate reuptake; and neurofilament Cytoskeleton organization. Predicted to be located in endoplasmic reticulum-Golgi intermediate compartment. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 8 and neuronal ceroid lipofuscinosis 8 northern epilepsy variant. Orthologous to human CLN8 (CLN8 transmembrane ER and ERGIC protein). [provided by Alliance of Genome Resources, Apr 2022]