2. Gene
  3. Irx4 - iroquois homeobox 4 Gene

Irx4 - iroquois homeobox 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 306655 | Gene type: protein coding

About Irx4

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in establishment of animal organ orientation. Predicted to be active in nucleus. Orthologous to human IRX4 (iroquois homeobox 4). [provided by Alliance of Genome Resources, Apr 2022]

Irx4 Products(1)

mRNA Protein Name
NM_001107330.2 NP_001100800.1 iroquois-class homeodomain protein IRX-4
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
18815185 RGD
Biological Process GO Annotation Evidence Reference Source
involved in establishment of animal organ orientation IEP
IEP: Inferred from expression pattern
10882515 RGD
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
18815185 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

iroquois-class homeodomain protein IRX-4

Iroquois related homeobox 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06923 IRX4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Irx4 NCBI NCBI:50805