2. Gene
  3. Fars2 - phenylalanyl-tRNA synthetase 2, mitochondrial Gene

Fars2 - phenylalanyl-tRNA synthetase 2, mitochondrial Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Fars1

Gene ID: 306879 | Gene type: protein coding

About Fars2

Summary

Predicted to enable phenylalanine-tRNA Ligase activity and tRNA binding activity. Predicted to be involved in phenylalanyl-tRNA aminoacylation and tRNA processing. Located in mitochondrion. Human ortholog(s) of this gene implicated in combined Oxidative Phosphorylation deficiency 14 and hereditary spastic paraplegia 77. Orthologous to human FARS2 (phenylalanyl-tRNA synthetase 2, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]

Fars2 Products(1)

mRNA Protein Name
NM_001013139.1 NP_001013157.1 phenylalanine--tRNA ligase, mitochondrial
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrion IDA
IDA: Inferred from direct assay
26553276 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phenylalanine--tRNA ligase, mitochondrial

pheRS

phenylalanine-tRNA synthetase 1 (mitochondrial)

phenylalanine-tRNA synthetase 2 (mitochondrial)

phenylalanyl-tRNA synthetase, mitochondrial

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04745 FAR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04748 FARS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22167 Far2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fars2 NCBI NCBI:10667