Fars2 - phenylalanyl-tRNA synthetase 2, mitochondrial Gene

Also Known as Fars1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 306879

Summary

Predicted to enable phenylalanine-tRNA Ligase activity and tRNA binding activity. Predicted to be involved in phenylalanyl-tRNA aminoacylation and tRNA processing. Located in mitochondrion. Human ortholog(s) of this gene implicated in combined Oxidative Phosphorylation deficiency 14 and hereditary spastic paraplegia 77. Orthologous to human FARS2 (phenylalanyl-tRNA synthetase 2, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]

Fars2 Products (1)

mRNA Protein Name
NM_001013139.1 NP_001013157.1 phenylalanine--tRNA ligase, mitochondrial
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
26553276 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phenylalanine--tRNA ligase, mitochondrial

  • pheRS

  • phenylalanine-tRNA synthetase 1 (mitochondrial)

  • phenylalanine-tRNA synthetase 2 (mitochondrial)

  • phenylalanyl-tRNA synthetase, mitochondrial

Orthologs Information

Species Symbol Source ID
Homo sapiens Fars2 NCBI NCBI:10667