Cttnbp2 - cortactin binding protein 2 Gene

Also Known as ORF4; Cortbp2; mKIAA1758; 6430526E05; 3010022N24Rik; 4732477G22Rik; 9130022E09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 30785

Summary

Predicted to enable SH3 domain binding activity and cytoskeletal regulatory protein binding activity. Predicted to be involved in regulation of modification of postsynaptic actin Cytoskeleton. Predicted to act upstream of or within actin Cytoskeleton organization. Located in glutamatergic synapse. Is active in postsynaptic actin Cytoskeleton. Is expressed in brain; dorsal grey horn; glans of male genital tubercle; intestine smooth muscle circular layer; and limb. Orthologous to human CTTNBP2 (cortactin binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Cttnbp2 Products (1)

mRNA Protein Name
NM_080285.2 NP_525024.1 cortactin-binding protein 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23015759 MGI
Cellular Component GO Annotation Evidence References Source
part of FAR/SIN/STRIPAK complex IDA
IDA: Inferred from direct assay
23015759 MGI
located in dendritic spine IDA
IDA: Inferred from direct assay
23015759 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
22262902 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
22262902 MGI
is active in postsynaptic actin cytoskeleton IDA
IDA: Inferred from direct assay
22262902 MGI
is active in postsynaptic actin cytoskeleton IMP
IMP: Inferred from mutant phenotype
22262902 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cortactin-binding protein 2

  • CTTNBP2 intron retention form

  • cortactin-binding protein 2 intron retention form

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03351 CTTNBP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03352 CTTNBP2NL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cttnbp2 NCBI NCBI:83992