Mmp20 - matrix metallopeptidase 20 (enamelysin) Gene

Mus musculus

Gene ID: 30800 | Gene type: protein coding

About Mmp20

Summary

This gene encodes a member of the matrix metalloproteinase family of zinc-dependent endopeptidases capable of degrading extracellular matrix proteins. This gene is expressed specifically in the ameloblasts and odontoblasts, and the encoded protein is an inactive zymogen that requires proteolytic removal of a N-terminal propeptide to become enzymatically active. Mice lacking the encoded protein display an amelogenesis imperfecta phenotype. [provided by RefSeq, Oct 2015]

Mmp20 Products(1)

mRNA	Protein	Name
NM_013903.2	NP_038931.1	matrix metalloproteinase-20 preproprotein

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within amelogenesis	IMP IMP: Inferred from mutant phenotype	15557396	MGI
acts upstream of or within extracellular matrix disassembly	IMP IMP: Inferred from mutant phenotype	22243248	MGI
acts upstream of or within protein catabolic process	IMP IMP: Inferred from mutant phenotype	22243248	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

matrix metalloproteinase-20

enamel metalloproteinase

matrix metalloproteinase 20 (enamelysin)

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08540	MMP20 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS08544	MMP25 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS19220	Mmp25 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mmp20	NCBI	NCBI:9313

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