2. Gene
  3. Lrrc4b - leucine rich repeat containing 4B Gene

Lrrc4b - leucine rich repeat containing 4B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Lrig4; NGL-3

Gene ID: 308571 | Gene type: protein coding

About Lrrc4b

Summary

Predicted to enable signaling receptor binding activity. Involved in regulation of postsynaptic density assembly; regulation of presynapse assembly; and synaptic membrane adhesion. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane. Orthologous to human LRRC4B (leucine rich repeat containing 4B). [provided by Alliance of Genome Resources, Apr 2022]

Lrrc4b Products(1)

mRNA Protein Name
NM_001271081.1 NP_001258010.1 leucine-rich repeat-containing protein 4B precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in regulation of postsynaptic density assembly IDA
IDA: Inferred from direct assay
19252495 RGD
involved in regulation of postsynaptic density assembly IMP
IMP: Inferred from mutant phenotype
19252495 RGD
involved in regulation of presynapse assembly IDA
IDA: Inferred from direct assay
19252495 RGD
involved in regulation of presynapse assembly IMP
IMP: Inferred from mutant phenotype
19252495 RGD
involved in synaptic membrane adhesion IDA
IDA: Inferred from direct assay
19252495 RGD
involved in synaptic membrane adhesion IMP
IMP: Inferred from mutant phenotype
19252495 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
19252495 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
19252495 RGD
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
19252495 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucine-rich repeat-containing protein 4B

netrin-G3 ligand

protein NGL-3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07821 LRRC4B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P992426 NS101 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lrrc4b NCBI NCBI:94030