2. Gene
  3. Ikbkg - inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Gene

Ikbkg - inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Nemo

Gene ID: 309295 | Gene type: protein coding

About Ikbkg

Summary

Enables peroxisome proliferator activated receptor binding activity. Predicted to be involved in several processes, including anoikis; regulation of gene expression; and regulation of signal transduction. Predicted to act upstream of or within B cell homeostasis and activation of NF-kappaB-inducing kinase activity. Located in cytosol. Part of IkappaB kinase complex. Used to study irritable bowel syndrome and perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in Behcet's disease; Bloch-Sulzberger syndrome; immunodeficiency 33; and learning disability. Orthologous to human IKBKG (inhibitor of nuclear factor kappa B kinase regulatory subunit gamma). [provided by Alliance of Genome Resources, Apr 2022]

Ikbkg Products(1)

mRNA Protein Name
NM_199103.2 NP_954534.1 NF-kappa-B essential modulator
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables peroxisome proliferator activated receptor binding IPI
IPI: Inferred from physical interaction
18828195 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
17419723 RGD
Cellular Component GO Annotation Evidence Reference Source
part of IkappaB kinase complex IDA
IDA: Inferred from direct assay
17419723 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NF-kappa-B essential modulator

I-kappa-B kinase gamma

I-kappa-B kinase subunit gamma

IKK-gamma

IKKAP1

IKKG

NF-kappa-B essential modifier

ikB kinase subunit gamma

ikB kinase-associated protein 1

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

inhibit

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06664 IKBKG Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ikbkg NCBI NCBI:8517