Zfyve27 - zinc finger FYVE-type containing 27 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 309376

Summary

Predicted to enable identical protein binding activity and protein self-association. Involved in neuron projection development; neurotrophin Trk Receptor signaling pathway; and protein localization to plasma membrane. Located in growth cone membrane and recycling endosome membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 33. Orthologous to human ZFYVE27 (zinc finger FYVE-type containing 27). [provided by Alliance of Genome Resources, Apr 2022]

Zfyve27 Products (1)

mRNA Protein Name
NM_199104.2 NP_954535.2 protrudin

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in neuron projection development IMP
IMP: Inferred from mutant phenotype
17082457 RGD
involved in neurotrophin TRK receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
17082457 RGD
involved in protein localization to plasma membrane IDA
IDA: Inferred from direct assay
17082457 RGD
Cellular Component GO Annotation Evidence References Source
located in growth cone membrane IDA
IDA: Inferred from direct assay
17082457 RGD
located in recycling endosome membrane IDA
IDA: Inferred from direct assay
17082457 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protrudin

  • zinc finger FYVE domain-containing protein 27

  • zinc finger, FYVE domain containing 27

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16060 ZFYVE27 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zfyve27 NCBI NCBI:118813