Zfyve27 - zinc finger FYVE-type containing 27 Gene

Rattus norvegicus

Gene ID: 309376 | Gene type: protein coding

About Zfyve27

Summary

Predicted to enable identical protein binding activity and protein self-association. Involved in neuron projection development; neurotrophin Trk Receptor signaling pathway; and protein localization to plasma membrane. Located in growth cone membrane and recycling endosome membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 33. Orthologous to human ZFYVE27 (zinc finger FYVE-type containing 27). [provided by Alliance of Genome Resources, Apr 2022]

Zfyve27 Products(1)

mRNA	Protein	Name
NM_199104.2	NP_954535.2	protrudin

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
involved in neuron projection development	IMP IMP: Inferred from mutant phenotype	17082457	RGD
involved in neurotrophin TRK receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	17082457	RGD
involved in protein localization to plasma membrane	IDA IDA: Inferred from direct assay	17082457	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in growth cone membrane	IDA IDA: Inferred from direct assay	17082457	RGD
located in recycling endosome membrane	IDA IDA: Inferred from direct assay	17082457	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

protrudin

zinc finger FYVE domain-containing protein 27

zinc finger, FYVE domain containing 27

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16060	ZFYVE27 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Zfyve27	NCBI	NCBI:118813

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