Rbm20 - RNA binding motif protein 20 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 309544

Summary

Predicted to enable mRNA binding activity. Involved in heart development and positive regulation of RNA splicing. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1DD. Orthologous to human RBM20 (RNA binding motif protein 20). [provided by Alliance of Genome Resources, Apr 2022]

Rbm20 Products (1)

mRNA Protein Name
NM_001107611.2 NP_001101081.2 RNA-binding protein 20

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables pre-mRNA intronic binding IDA
IDA: Inferred from direct assay
24960161 RGD
Biological Process GO Annotation Evidence References Source
involved in heart formation IDA
IDA: Inferred from direct assay
23307558 RGD
involved in heart formation IMP
IMP: Inferred from mutant phenotype
22466703 RGD
involved in negative regulation of mRNA splicing, via spliceosome IDA
IDA: Inferred from direct assay
23307558 RGD
involved in negative regulation of mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
35394688 RGD
involved in regulation of RNA splicing IMP
IMP: Inferred from mutant phenotype
22466703 RGD
involved in regulation of alternative mRNA splicing, via spliceosome IDA
IDA: Inferred from direct assay
27289039 RGD
involved in regulation of alternative mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
33805770 RGD
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic ribonucleoprotein granule IDA
IDA: Inferred from direct assay
35394688 RGD
is active in nucleus IDA
IDA: Inferred from direct assay
23307558 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RNA-binding protein 20

  • probable RNA-binding protein 20

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11739 RBM20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rbm20 NCBI NCBI:282996