Atp6v1b1 - ATPase H+ transporting V1 subunit B1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 312488

Summary

Predicted to enable proton transmembrane transporter activity. Predicted to be involved in several processes, including cation homeostasis; sensory perception of sound; and vacuolar proton-transporting V-type ATPase complex assembly. Predicted to act upstream of or within several processes, including inorganic ion homeostasis; renal sodium ion transport; and renal water homeostasis. Located in apical plasma membrane; basolateral plasma membrane; and synaptic vesicle. Is extrinsic component of synaptic vesicle membrane. Human ortholog(s) of this gene implicated in renal tubular acidosis. Orthologous to human ATP6V1B1 (ATPase H+ transporting V1 subunit B1). [provided by Alliance of Genome Resources, Apr 2022]

Atp6v1b1 Products (1)

mRNA Protein Name
NM_001107867.2 NP_001101337.2 V-type proton ATPase subunit B, kidney isoform

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
10748165 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
17959750 RGD
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
9192637 RGD
is active in extrinsic component of synaptic vesicle membrane EXP
EXP: Inferred from Experiment
23622064 RGD
is active in extrinsic component of synaptic vesicle membrane IDA
IDA: Inferred from direct assay
23622064 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

V-type proton ATPase subunit B, kidney isoform

  • ATPase, H transporting, lysosomal V1 subunit B1

  • ATPase, H+ transporting, V1 subunit B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01224 ATP6V1B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atp6v1b1 NCBI NCBI:525