Tmem67 - transmembrane protein 67 Gene

Also Known as Wpk; Mks3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 313067

Summary

Meckelin is mutated in the wpk rat. [provided by RefSeq, Jul 2008]

Tmem67 Products (1)

mRNA Protein Name
NM_001107916.2 NP_001101386.3 meckelin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables misfolded protein binding IDA
IDA: Inferred from direct assay
19815549 RGD
Biological Process GO Annotation Evidence References Source
involved in cilium assembly IMP
IMP: Inferred from mutant phenotype
19515853 RGD
involved in head development IMP
IMP: Inferred from mutant phenotype
30705305 RGD
involved in negative regulation of centrosome duplication IMP
IMP: Inferred from mutant phenotype
19515853 RGD
involved in photoreceptor cell outer segment organization IMP
IMP: Inferred from mutant phenotype
23516626 RGD
involved in positive regulation of ERAD pathway IMP
IMP: Inferred from mutant phenotype
19815549 RGD
involved in positive regulation of non-motile cilium assembly IMP
IMP: Inferred from mutant phenotype
21614130 RGD
Cellular Component GO Annotation Evidence References Source
located in axoneme IDA
IDA: Inferred from direct assay
23516626 RGD
located in cytoplasmic vesicle membrane IDA
IDA: Inferred from direct assay
19815549 RGD
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
19815549 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

meckelin

  • Meckel syndrome type 3 protein homolog

  • Wistar polycystic kidney

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14737 TMEM67 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmem67 NCBI NCBI:91147