Tmem67 - transmembrane protein 67 Gene

Rattus norvegicus

Also known as Wpk; Mks3

Gene ID: 313067 | Gene type: protein coding

About Tmem67

Summary

Meckelin is mutated in the wpk rat. [provided by RefSeq, Jul 2008]

Tmem67 Products(1)

mRNA	Protein	Name
NM_001107916.2	NP_001101386.3	meckelin

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables misfolded protein binding	IDA IDA: Inferred from direct assay	19815549	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cilium assembly	IMP IMP: Inferred from mutant phenotype	19515853	RGD
involved in head development	IMP IMP: Inferred from mutant phenotype	30705305	RGD
involved in negative regulation of centrosome duplication	IMP IMP: Inferred from mutant phenotype	19515853	RGD
involved in photoreceptor cell outer segment organization	IMP IMP: Inferred from mutant phenotype	23516626	RGD
involved in positive regulation of ERAD pathway	IMP IMP: Inferred from mutant phenotype	19815549	RGD
involved in positive regulation of non-motile cilium assembly	IMP IMP: Inferred from mutant phenotype	21614130	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in axoneme	IDA IDA: Inferred from direct assay	23516626	RGD
located in cytoplasmic vesicle membrane	IDA IDA: Inferred from direct assay	19815549	RGD
located in endoplasmic reticulum membrane	IDA IDA: Inferred from direct assay	19815549	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

meckelin

Meckel syndrome type 3 protein homolog

Wistar polycystic kidney

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14737	TMEM67 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tmem67	NCBI	NCBI:91147

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