Whrn - whirlin Gene

Enables protein domain specific binding activity. Predicted to be involved in several processes, including detection of mechanical stimulus involved in sensory perception of sound; nervous system development; and paranodal junction maintenance. Predicted to act upstream of or within establishment of protein localization and positive regulation of gene expression. Located in several cellular components, including dendrite; stereocilia ankle link; and stereocilium tip. Colocalizes with neuronal cell body; photoreceptor connecting cilium; and photoreceptor inner segment. Human ortholog(s) of this gene implicated in Usher syndrome type 2D; autosomal recessive nonsyndromic deafness 31; and sensorineural hearing loss. Orthologous to human WHRN (whirlin). [provided by Alliance of Genome Resources, Apr 2022]