2. Gene
  3. SPTB - Sptb spectrin, beta, erythrocytic Gene

SPTB - Sptb spectrin, beta, erythrocytic Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Spnb1

Gene ID: 314251 | Gene type: protein coding

About SPTB

Summary

Predicted to enable actin filament binding activity and ankyrin binding activity. Predicted to be involved in actin Cytoskeleton organization. Predicted to act upstream of or within hemopoiesis; plasma membrane organization; and porphyrin-containing compound biosynthetic process. Predicted to be located in several cellular components, including cell surface; cytoskeleton; and cytosol. Predicted to be part of protein-containing complex. Predicted to be active in several cellular components, including cell junction; cortical actin cytoskeleton; and plasma membrane. Human ortholog(s) of this gene implicated in hereditary spherocytosis and hereditary spherocytosis type 2. Orthologous to human SPTB (spectrin beta, erythrocytic). [provided by Alliance of Genome Resources, Apr 2022]

SPTB Products(1)

mRNA Protein Name
NM_212522.1 NP_997687.1 spectrin beta chain, erythrocytic
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
11454415 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
11454415 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

spectrin beta chain, erythrocytic

erythroid spectrin beta

spectrin beta 1

spectrin beta chain, erythrocyte

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13731 SPTB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens SPTB NCBI NCBI:6710