SPTB - Sptb spectrin, beta, erythrocytic Gene

Predicted to enable actin filament binding activity and ankyrin binding activity. Predicted to be involved in actin Cytoskeleton organization. Predicted to act upstream of or within hemopoiesis; plasma membrane organization; and porphyrin-containing compound biosynthetic process. Predicted to be located in several cellular components, including cell surface; cytoskeleton; and cytosol. Predicted to be part of protein-containing complex. Predicted to be active in several cellular components, including cell junction; cortical actin cytoskeleton; and plasma membrane. Human ortholog(s) of this gene implicated in hereditary spherocytosis and hereditary spherocytosis type 2. Orthologous to human SPTB (spectrin beta, erythrocytic). [provided by Alliance of Genome Resources, Apr 2022]