Mapk8ip2 - mitogen-activated protein kinase 8 interacting protein 2 Gene

Also Known as IB-2; JIP-2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 315220

Summary

Predicted to enable several functions, including MAP-kinase scaffold activity; Kinesin binding activity; and protein kinase activator activity. Involved in positive regulation of stress-activated MAPK cascade. Part of protein-containing complex. Orthologous to human MAPK8IP2 (mitogen-activated protein kinase 8 interacting protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Mapk8ip2 Products (1)

mRNA Protein Name
NM_001100720.2 NP_001094190.1 C-Jun-amino-terminal kinase-interacting protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22128169 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
12024021 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of stress-activated MAPK cascade IMP
IMP: Inferred from mutant phenotype
12024021 RGD
Cellular Component GO Annotation Evidence References Source
part of protein-containing complex IDA
IDA: Inferred from direct assay
12024021 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-Jun-amino-terminal kinase-interacting protein 2

  • JNK MAP kinase scaffold protein 2

  • JNK-interacting protein 2

  • islet-brain-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08125 MAPK8IP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mapk8ip2 NCBI NCBI:23542